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Peptide articles
and guides
Easy-to-read articles on peptide research, dosing, mixing, and the science behind it all.
## Oral KPV in Nanoparticles Reduced Stomach Inflammation. " Lysine-proline-valine (KPV), a naturally occurring tripeptide, has been shown to attenuate the inflammatory responses of colonic cells." (1) "Intriguingly, we found that HA-KPV-NPs exert combined effects against UC by **both accelerating mucosal healing and alleviating inflammation**. Oral administration of HA-KPV-NPs encapsulated in a hydrogel (chitosan/alginate) exhibited a much stronger
It may seem like research interest in melanotan 2 and other melanocortin receptor agonists has fallen off of a cliff, but nothing could be farther from the truth. For those people who follow the most recent publications, it is clear that there is still a great deal of interest in melanotan II. Research papers on the ability of this peptide to improve heart function, counteract obesity, boost thermogenesis, and regulate energy homeostasis have all been published within the last 12 years. Resea
## Hexarelin vs Ipamorelin: Best Guide in 2024 Hexarelin (a.k.a. examorelin) is a synthetic analogue of ghrelin as is ipamorelin. The two peptides are therefore both growth hormone secretagogue receptor agonists. Ipamorelin is just five amino acids long while hexarelin is six. Despite their similar derivation and near identical size, hexarelin and ipamorelin have some important differences. Hexare
## What Are SARMs? SARM stands for selective androgen receptor modulator. This simply means that SARMs are androgen receptor ligands and can therefore bind to androgen receptors A and B. You might think that this means that testosterone is technically a SARMs, but this isn’t the case. Testosterone doesn’t fall into this category because, even though it binds to androgen receptors, it is not selective in its effects. It is this selectivity in action that makes SARMs so useful. Testosterone,
## MOTS-c Doubles Running Capacity of Old Mice. “See how they run: ‘Exercise protein’ doubles running capacity, restores function and extends healthy lifespans in older mice Animal and human data reveal new target for reversing age-related decline, according to USC study.” See how they run: ‘Exercise protein’ doubles running capacity & extends healthy lifespan in old mice - YouTube [Photo image of USC Leonard Davis School of Gerontology](https://www.youtube.com/ch
Bone Density / OsteoporosisCellular Energy (Mitochondrial Function)Insulin Sensitization (Blood Sugar Stabilization)
" **Clearance of damaged tissue can facilitate renal repair and promote immune tolerance. Therefore, the augmentation of phagocytosis of macrophages is likely to be one of the mechanisms for the renoprotective effect of EPO as well. Such hypothesis does not contradict with our study, in which we focused the functional switch of macrophages.**" "Commonly defined by _in vitro_ experiments, macrophage activation can be distinguished for two major subtypes: classically activated M1 macrophages ar
## BPC 157 Arginate vs BPC 157 Acetate Another way to evaluate the quality of a BPC 157 source is to look at whether the seller understands the difference between the arginate and acetate versions of the peptide. BPC 157 acetate is a slightly modified version of the natural peptide that provides for increased shelf-life and better resistance to the extremes of shipping environments. BPC 157 acetate is commonly used for subcutaneous injection as it
## Sermorelin vs. CJC-1295 Structure Below are the structures of sermorelin and CJC-1295 laid out in various formats. Notice that sermorelin is simply GHRH 1-29. That is to say, sermorelin is simply the first 29 amino acids from the much larger growth hormone-releasing hormone. CJC-1295 is also made up of the first 29 amino acids of GHRH, but some of the amino acids have been modified.
## NNMT Inhibitor Caused Weight Loss and Reduced Adipose Tissue Mass in Mice. "Consistent with these results, histological analysis of the EWAT [epididymal white adipose tissue] from treated DIO mice had 1. "> 30% decrease in adipocyte size... 2. > 40% decrease in adipocyte volume (data not shown) compared to control DIO mice... 3. Plasma lipid-profile measurements showed that the total cholesterol levels were ~30% lower in treated DIO mice relative to control DIO mice... 4. D
5-Amino-1MQCellular Energy (Mitochondrial Function)
### MOTS-c treatment enhances physical excercise capacity. "Aging is accompanied by a progressive decline in mitochondrial function and loss of metabolic homeostasis, in which MOTS-c may play a role. Aging is associated with reduced MOTS-c levels in certain tissues, including the skeletal muscle, and in circulation. We previously showed that an acute one-week MOTS-c treatment reversed age-dependent insulin resistance in mouse skeletal muscle. Thus, we investigated if promoting metabolic homeost
Cellular Energy (Mitochondrial Function)Insulin Sensitization (Blood Sugar Stabilization)MOTS-c
BPC 157 is a peptide that has demonstrated anti-inflammatory, cytoprotective, and endothelial-protective effects in different organ systems in different species. BPC 157 activated endothelial nitric oxide synthase (eNOS) is associated with nitric oxide (NO) release, tissue repair and angio-modulatory properties which can lead to improved vascular integrity and immune response, reduced proinflammatory profile, and reduced critical levels of the disea
BPC-157Immune FunctionRepair and Recovery Research