Hexarelin protects heart cells from hypertrophy by stimulating autophagy
“Ang-II induced cardiomyocyte hypertrophy, oxidative stress, apoptosis and decreased cell survival, all of which were significantly suppressed by hexarelin (a growth hormone peptide) treatment which also enhanced autophagy in hypertrophic H9C2 cells.” " Hexarelin is a synthetic growth hormone-releasing peptide that exerts cardioprotective effects. Regulation of autophagy is known to be cardioprotective so this study examined the role o