### MOTS-c treatment enhances physical excercise capacity. "Aging is accompanied by a progressive decline in mitochondrial function and loss of metabolic homeostasis, in which MOTS-c may play a role. Aging is associated with reduced MOTS-c levels in certain tissues, including the skeletal muscle, and in circulation. We previously showed that an acute one-week MOTS-c treatment reversed age-dependent insulin resistance in mouse skeletal muscle. Thus, we investigated if promoting metabolic homeost
Cellular Energy (Mitochondrial Function)
Insulin Sensitization (Blood Sugar Stabilization)
MOTS-c
## MOTS-c Doubles Running Capacity of Old Mice. “See how they run: ‘Exercise protein’ doubles running capacity, restores function and extends healthy lifespans in older mice Animal and human data reveal new target for reversing age-related decline, according to USC study.” See how they run: ‘Exercise protein’ doubles running capacity & extends healthy lifespan in old mice - YouTube [Photo image of USC Leonard Davis School of Gerontology](https://www.youtube.com/ch
Bone Density / Osteoporosis
Cellular Energy (Mitochondrial Function)
Insulin Sensitization (Blood Sugar Stabilization)
How Does MOTS-c Affect Performance? It is widely accepted that regular physical activity is beneficial for cardiovascular health. Frequent exercise is robustly associated with a decrease in cardiovascular mortality as well as the risk of developing cardiovascular disease (CVD). Physically active individuals have lower blood pressure, higher insulin sensitivity, and a more favorable plasma lipoprotein profile. Animal models of exercise show that repea
Cardiac Function
Cellular Energy (Mitochondrial Function)
Insulin Sensitization (Blood Sugar Stabilization)
Cardiac Function
Cellular Energy (Mitochondrial Function)
MOTS-c
1. **Metabolic Disorders**: MOTS-c's capacity to enhance insulin sensitivity and ameliorate glucose metabolism offers promising avenues for addressing metabolic disorders. Studies suggest its potential in mitigating the underlying pathophysiological processes associated with conditions like type 2 diabetes and obesity. 2. **Health Issues Related to Aging**: Age-related ailments are often linked to mitochondrial dysfunction and oxidative stress. MOTS-c's ability to uphold mitochondrial integrity
MOTS-c