Peptide articles and guides

How Does the SHMOOSE Protein Affect Brain Plaques in Alzheimer’s Disease?

## SHMOOSE microprotein, a novel mitochondrial DNA variation connected to Alzheimer’s Disease pathology Alzheimer's is a disease that has recently caught the attention of researchers because of the alarming increase in cases through the years. [1,7] This rare but common disorder affects around 6.07 million people in 2020 in the United States. [5] Now, there is no cure for AD. [7] The complexity of AD pathology makes it challenging for investigators to find solutions like treatments for th

Amylin Protein Targets Alzheimer’s disease

## The remarkable benefits of amylin protein as a treatment for Alzheimer's disease Alzheimer's disease (AD) is known to be a multifactorial disease. [2] That is, several factors contribute to the pathogenic development of this disorder. However, amyloid beta ( **Aβ**) accumulation in the brain is highlighted as critical in developing the disease. [2,3] Recent studies have shown that long before the onset of symptoms of the disease, the accumulation of the Aβ protein forms plaques between

The Role of Cell-Permeable Peptides and The JNK Family in Preventing Neuronal Degeneration

## Figure 1:     Neuroprotective features of CPPs in combination with other molecules or peptides for treating PD and AD.

The Optimal Performance of AmyP53 Peptide for Alzheimer’s and Parkinson’s Disease

Recent studies suggest a different approach to elaborating therapies for these neurodegenerative disorders. In general, one of the typical pathological hallmarks of Parkinson’s (PD) and Alzheimer’s disease (AD) is the misfolding and accumulation of specific proteins like the α-synuclein and the β-amyloid, which, in high levels, are detrimental to the brain cells.[4] Even though most of the research effort is used to prevent the accumulation of these proteins, there is still no cure for neurode

Peptides and Cognitive Decline during the Aging Process

As we embark on the journey of life, our minds serve as the compass guiding us through a myriad of experiences and memories. However, with the passing of time, the aging process can cast a shadow on this cognitive prowess. Cognitive decline, a natural part of growing older, has long been a concern for individuals seeking to maintain mental acuity and preserve their quality of life. Fortunately, as scientific research advances, new avenues of exploration emerge, shedding light on potential soluti

Cdk5i Peptide Mitigates Neurodegeneration Seen in Alzheimer’s Disease

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V24P Peptide Targets Amyloid Plaques in Alzheimer’s Disease

## Mechanism of the V24P (10-40) scavenger peptide.

Curcumin-loaded PLGA Nanoparticles Improve Cognition and Neurogenesis in Alzheimer’s

Lipid Nanoparticles Deliver RNA to the Brain for Alzheimer’s

Neurodegenerative disorders are typically linked to chronic neuroinflammation. Alzheimer’s disease (AD) is not an exception since chronic inflammation is one of the hallmarks that contributes to the progression of the disorder.[2] Microglia cells are the main characters in promoting neuroinflammation since they are the most abundant brain immune cells. [2-5] Microglia cells are well known to clear different waste materials from the brain and confer neuroprotection (see Fig.1).[6] However,