Cognition is a complex system encompassing processes such as episodic memory, working memory, executive function/inhibition, spatial learning, language/vocabulary comprehension, processing speed, and language/reading decoding. Changes in synaptic plasticity, the ability of the brain to change and adapt to new information, can be short lived from milliseconds to years. Short lived forms include facilitation, augmentation, and potentiation which enhances neurotransmitter release. These dynamic cha
Semax Research: Memory Enhancement and Brain Protection
"Here, we found that a single application of Semax (50 μg/kg body weight) results in a maximal **1.4-fold increase of BDNF protein levels accompanying with 1.6-fold increase of trkB tyrosine phosporylation levels, and a 3-fold and a 2-fold increase of exon III BDNF and trkB mRNA levels, respectively, in the rat hippocampus.** Semax-treated animals showed a distinct increase in the number of conditioned avoidance reactions. We suggest that Semax affec