CJC-1295 + GHRP-2 (10mg Blend) dosing guide
This blend pairs CJC-1295's long-lasting GH elevation with GHRP-2's quick, powerful GH bursts. GHRP-2 triggers fast GH spikes, while CJC-1295 keeps levels elevated for hours. Note: GHRP-2 may increase your appetite more than Ipamorelin would.
Think of it like: Think of it like a rocket launch. GHRP-2 is the initial explosive boost that shoots you into the sky quickly. CJC-1295 is the sustained engine that keeps you flying high for hours. Together, you get both the immediate 'blast off' AND the long-lasting altitude!
CJC-1295 is a long-acting GHRH analog that elevates GH levels 2-10× baseline for approximately 6 days. GHRP-2 is a ghrelin-mimetic secretagogue that triggers rapid GH pulses peaking within ~25 minutes of administration. Combining these leverages GHRP-2's acute pulsatile release with CJC-1295's sustained action.
GH Release Cycle
Secretagogues trigger pulsatile growth hormone release from the pituitary.
Quickstart Highlights
- Dosage: 100-300mcg
- Frequency: 1-2x daily
- Administration: Subcutaneous
- Cycle length: 8-12 weeks
Dosing Plan
| Weeks | Dose | Units |
|---|---|---|
| Weeks 1–2 | 100mcg blend once daily | 3 units (0.03mL) |
| Weeks 3–8 | 200mcg blend 1-2x daily | 6 units per dose |
| Weeks 9–12 | 300mcg blend 1-2x daily | 9 units per dose |
How to mix
Add 3.0mL bacteriostatic water → ~3.33mg/mL concentration
- Draw 3.0mL bacteriostatic water with a sterile syringe.
- Inject slowly down the vial wall.
- Gently swirl until dissolved.
- Label with date and refrigerate at 2–8°C; use within 2-4 weeks.
Syringe Math Reference
- 10mg vial with 3mL BAC water = 3.33 mg/mL
- 1 unit = 0.01mL ≈ 33.3mcg blend
- 100mcg = 3 units
- 200mcg = 6 units
- 300mcg = 9 units
What you'll need
Blend Vials (10mg)
- 4 weeks 1-2 vials
- 8 weeks 3-4 vials
- 12 weeks 5-6 vials
Insulin Syringes (U-100)
- 4 weeks 30-60 syringes
- 12 weeks 90-180 syringes
Bacteriostatic Water (10mL)
- 12 weeks 2 bottles
Alcohol Swabs
- 12 weeks 2 × 100-count boxes
How This Works
CJC-1295 is a GHRH analog that produces sustained GH and IGF-1 elevation lasting several days. GHRP-2 is a ghrelin mimetic that triggers rapid, acute GH pulses within minutes of injection. Combining these creates synergy: GHRP-2 provides the acute pulse while CJC-1295 amplifies and sustains the response.
CJC-1295
5mgLong-acting GHRH analog for sustained GH and IGF-1 elevation
GHRP-2
5mgGhrelin mimetic for rapid GH pulses with moderate appetite increase
Mechanism of Action
How CJC-1295 Works in Your Body
Peptide Administered
Enters bloodstream via subcutaneous injection
Pituitary Activation
Stimulates the pituitary gland to release GH
GH Pulse
Natural growth hormone pulse is amplified
Tissue Response
Muscles repair, bones strengthen, fat reduces
Benefits & Side Effects
Potential Benefits
- Synergistic GH release
- Sustained GH elevation
- Rapid acute pulses
- Improved recovery
- Better body composition
Potential Side Effects
- Increased appetite (GHRP-2 effect)
- Water retention
- Numbness/tingling
- Elevated cortisol/prolactin (moderate)
How to store it
- Lyophilized: Refrigerate or freeze at −20°C.
- Reconstituted: Refrigerate at 2–8°C; use within 2-4 weeks.
Good to know
- GHRP-2 provides moderate appetite increase.
- Must be taken on empty stomach.
- CJC provides sustained baseline, GHRP-2 provides acute pulses.
- Synergistic GH release when combined.
- Space doses at least 3 hours apart if taking multiple times daily.
References
Community Insights
Summarised from 2 sourcesCJC-1295 is a long-acting GHRH analog that elevates GH levels 2-10× baseline for approximately 6 days. GHRP-2 is a ghrelin-mimetic secretagogue that triggers rapid GH pulses peaking within ~25 minutes of administration. Combining these leverages GHRP-2's acute pulsatile release with CJC-1295's sust
Common Dosages Reported
- 100-300mcg 1-2x daily
- Standard protocol dosing
Side Effects Mentioned
- Generally mild, individual variation expected
- See full guide for detailed safety info
Stacking Suggestions
- Consult research and healthcare provider before stacking
What people are saying
Results vary based on individual response
Consistent dosing and timing important
Reviews & Discussion
Real experiences shared by the community — not medical advice.
CJC-1295 + GHRP-2 for Narcolepsy Symptoms
A user noted that using CJC-1295 and GHRP-2 was helpful for addressing symptoms of narcolepsy and excessive daytime sleepiness. They experienced an increase in energy and a reduction in the need for daytime naps while using the combination.
CJC-1295 Stacking Synergies
A user inquired about the benefits of stacking CJC-1295, with several contributors noting that it is most effective when paired with a GHRP like GHRP-2 or GHRP-6. The discussion highlighted that the combination creates a synergistic effect on growth hormone pulses compared to using either alone.
MK677 and CJC-1295 DAC Cycle Log
A user conducting a long-term log reported significant benefits from combining MK677 with CJC-1295 (with DAC). They experienced improved sleep quality, increased muscular fullness, and better recovery during their cycle.
Dose-Dependent Flushing Response
An experienced member confirmed that a 'CJC Flush' is a common, dose-dependent side effect of the peptide. They noted that at higher dosages, such as 1mg, the flush is very prominent and can also affect breathing and heart rate temporarily.
CJC-1295 DAC for Performance and Longevity
A user noted that CJC-1295 with DAC is effective for performance when used at dosages of 2mg per week or higher. They suggested it as a viable option for long-term use during cruise phases of a TRT regimen.
Acute Flushing and Heart Rate Increase
A user reported experiencing a 'heat wave' or intense flushing sensation immediately after injecting a 600mcg dose of CJC-1295. This was accompanied by an increased heart rate and a sensation similar to vasoconstriction.
Long-term Combination Experiment Starting
A user initiated a six-month experiment using a combination of Modified GRF 1-29 (CJC-1295 No DAC) and GHRP-2. The user opted to dose the peptides twice daily, once upon waking and once before bed, to evaluate the long-term effectiveness of the therapy for growth hormone optimization.
CJC-1295/GHRP Pulse Generation Comparison
A user compared the effects of MK-677 to a CJC-1295 and GHRP combo, noting that while MK-677 enhances natural growth hormone pulses, the peptide combination is more effective at actively instigating those pulses.
CJC-1295 / Ipamorelin / GHRP-2 Blend and Tirzepatide Stack
A user combined a blend of CJC-1295, Ipamorelin, and GHRP-2 with Tirzepatide for weight loss and muscle growth goals. While the user reported significant weight loss since starting their overall regimen, the specific impact of the peptide blend relative to the Tirzepatide was not detailed.
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