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Adipotide 1 min read January 28, 2026

What is Adipotide?

[Adipotide](http://www.news-medical.net/news/20120711/Arrowhead-initiates-Adipotide-Phase-1-trial-in-obesity.aspx "adipotide") is a peptidomimetic compound that has been shown to possess pro-apoptotic properties that do cause weight loss in rhesus monkeys and mice. Its sequence is CKGGRAKDC-GG-D(KLAKLAK)2. Studies have shown that its mode of action involves the selective apoptosis of blood vessels supplying the white adipose tissue. [Adipotide](

[Adipotide](http://www.news-medical.net/news/20120711/Arrowhead-initiates-Adipotide-Phase-1-trial-in-obesity.aspx "adipotide") is a peptidomimetic compound that has been shown to possess pro-apoptotic properties that do cause weight loss in rhesus monkeys and mice. Its sequence is CKGGRAKDC-GG-D(KLAKLAK)2. Studies have shown that its mode of action involves the selective apoptosis of blood vessels supplying the white adipose tissue. [Adipotide](

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Adipotide (FTPP)

Pro-apoptotic peptidomimetic that targets blood vessels of white adipose tissue. Caused rapid weight loss and improved insulin resistance in obese monkeys but produced mild reversible renal injury.

Fat loss research Adipose vasculature targeting

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