Adrenocorticotropic hormone that stimulates the adrenal cortex to secrete cortisol and other glucocorticoids. Secretion follows circadian rhythm and increases with stress. Used diagnostically as cosyntropin.
Endocrine Signaling
Hormonal peptides modulate release along the endocrine axis.
Quickstart Highlights
- Dosage: Diagnostic doses
- Frequency: Per medical plan
- Administration: Intravenous or intramuscular
- Cycle length: Per medical plan
How This Works
Mechanism of Action
How ACTH Works in Your Body
Peptide Administered
Enters the bloodstream via injection
Receptor Binding
Finds and activates its target receptor
Signal Cascade
Triggers a chain of cellular responses
Biological Effect
The body produces the desired outcome
Benefits & Side Effects
Potential Benefits
- Adrenal function testing
- Cortisol stimulation
- Diagnostic use
Quick notes
Not a performance peptide. Diagnostic and occasionally therapeutic (infantile spasms).
References
Community Insights
Summarised from 1 sourceAdrenocorticotropic hormone that stimulates the adrenal cortex to secrete cortisol and other glucocorticoids. Secretion follows circadian rhythm and increases with stress. Used diagnostically as cosyntropin. Not a performance peptide. Diagnostic and occasionally therapeutic (infantile spasms).
Common Dosages Reported
- Diagnostic doses Per medical plan
- Standard protocol dosing
Side Effects Mentioned
- Generally mild, individual variation expected
- See full guide for detailed safety info
Stacking Suggestions
- Consult research and healthcare provider before stacking
What people are saying
Results vary based on individual response
Consistent dosing and timing important
Reviews & Discussion
Real experiences shared by the community — not medical advice.
Positive anticipation for ACTH 1-39 function
A user expressed significant excitement about the potential of ACTH 1-39, referring to it as an awesome addition to the peptide market. They specifically highlighted its role in stimulating adrenal function and its potential application in recovery protocols.
Inquiry regarding ACTH (1-39) hormonal and cognitive effects
The poster shares that ACTH (1-39) is hormonally active and is purported to increase BDNF levels while stimulating the dopaminergic and serotoninergic systems. They mention its potential for cognitive enhancement but express concern regarding its hormonal activity.
ACTH for MS and Seizures
A user shared that their friend uses ACTH 1-39 to manage multiple sclerosis (MS) relapses with successful results. The friend reported that the peptide also assists with seizures and promotes neuronal regeneration.
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