CJC-1295 NO DAC + Ipamorelin (10mg Blend) dosing guide
This is the 'clean' version of the most popular GH peptide combo! The 'NO DAC' version of CJC-1295 creates natural GH pulses (not constant elevation), and Ipamorelin is the cleanest GH-releaser with no hunger or stress hormone increases. Perfect for beginners.
Think of it like: If regular CJC-1295 is like leaving a faucet running all day, the NO DAC version is like turning it on and off naturally. Combined with Ipamorelin (the 'gentleman' of GH peptides that doesn't cause side effects), you get the most natural-feeling GH boost possible!
This blend combines CJC-1295 (no DAC), a modified growth hormone-releasing hormone (GHRH) analog, with Ipamorelin, a selective growth hormone secretagogue (GHS). CJC-1295 (no DAC) produces sustained, dose-dependent GH and IGF-1 increases, while Ipamorelin selectively stimulates GH release without raising ACTH or cortisol.
GH Release Cycle
Secretagogues trigger pulsatile growth hormone release from the pituitary.
Quickstart Highlights
- Dosage: 100-300mcg each
- Frequency: 1-2x daily
- Administration: Subcutaneous
- Cycle length: 8-16 weeks
Dosing Plan
| Weeks | Dose | Units |
|---|---|---|
| Weeks 1–2 | 100mcg each once daily | 6 units (0.06mL) |
| Weeks 3–8 | 200mcg each 1-2x daily | 12 units per dose |
| Weeks 9–16 | 300mcg each 1-2x daily | 18 units per dose |
How to mix
Add 3.0mL bacteriostatic water → ~3.33mg/mL total (1.67mg/mL each)
- Draw 3.0mL bacteriostatic water with a sterile syringe.
- Inject slowly down the vial wall.
- Gently swirl until dissolved.
- Label with date and refrigerate at 2–8°C.
Syringe Math Reference
- 10mg vial with 3mL BAC water = 3.33 mg/mL total
- Each peptide: 1.67 mg/mL
- 1 unit = 0.01mL ≈ 33.3mcg total (16.7mcg each)
- 100mcg each = 6 units
- 200mcg each = 12 units
- 300mcg each = 18 units
What you'll need
Blend Vials (10mg)
- 4 weeks 2-3 vials
- 8 weeks 4-6 vials
- 16 weeks 8-12 vials
Insulin Syringes (U-100)
- 4 weeks 30-60 syringes
- 16 weeks 120-240 syringes
Bacteriostatic Water (10mL)
- 16 weeks 3-4 bottles
Alcohol Swabs
- 16 weeks 3 × 100-count boxes
How This Works
CJC-1295 NO DAC (Mod GRF 1-29) is a GHRH analog that stimulates GH release from the pituitary. Ipamorelin is a ghrelin mimetic that selectively releases GH without affecting cortisol or appetite. Together, they create synergistic GH release that mimics natural pulsatile patterns while providing enhanced amplitude.
CJC-1295 NO DAC (Mod GRF 1-29)
5mgModified GHRH analog for GH release without extended half-life
Ipamorelin
5mgSelective GH secretagogue without cortisol or appetite effects
Mechanism of Action
How CJC-1295 Works in Your Body
Peptide Administered
Enters bloodstream via subcutaneous injection
Pituitary Activation
Stimulates the pituitary gland to release GH
GH Pulse
Natural growth hormone pulse is amplified
Tissue Response
Muscles repair, bones strengthen, fat reduces
Benefits & Side Effects
Potential Benefits
- Synergistic GH release
- Clean profile - no cortisol/hunger effects
- Improved sleep quality
- Enhanced recovery
- Anti-aging benefits
- Better body composition
Potential Side Effects
- Injection site reactions (mild)
- Headache (rare)
- Water retention (mild)
- Generally very well tolerated
How to store it
- Lyophilized: Freeze at −20°C (−4°F).
- Reconstituted: Refrigerate at 2–8°C.
- Avoid freeze–thaw cycles.
Good to know
- Most popular GH peptide combination.
- Cleanest GH peptide blend (no cortisol, no hunger increase).
- NO DAC version has shorter half-life (for acute pulses).
- Take on empty stomach for best results.
- Can be run for extended periods safely.
Community Insights
Summarised from 3 sourcesThis blend combines CJC-1295 (no DAC), a modified growth hormone-releasing hormone (GHRH) analog, with Ipamorelin, a selective growth hormone secretagogue (GHS). CJC-1295 (no DAC) produces sustained, dose-dependent GH and IGF-1 increases, while Ipamorelin selectively stimulates GH release without ra
Common Dosages Reported
- 100-300mcg each 1-2x daily
- Standard protocol dosing
Side Effects Mentioned
- Generally mild, individual variation expected
- See full guide for detailed safety info
Stacking Suggestions
- Consult research and healthcare provider before stacking
What people are saying
Results vary based on individual response
Consistent dosing and timing important
Reviews & Discussion
Real experiences shared by the community — not medical advice.
Sleep and Recovery Improvement with CJC-1295/Ipamorelin
A user added CJC-1295 (without DAC) and Ipamorelin to their existing peptide regimen. They reported that the combination significantly improved their sleep quality and enhanced their recovery from physical activity.
Sleep and Body Composition Improvements
One forum member recommended the stack for its ability to improve sleep quality and aid in body composition goals, such as staying lean or adding mass. They specifically advised using the No DAC version of CJC-1295 to better mimic natural growth hormone pulses.
Synergistic Benefits of Stacking CJC-1295 and Ipamorelin
A user noted that combining CJC-1295 with Ipamorelin is highly effective because they work synergistically to maximize growth hormone release. They described the combination as a 'powerhouse' that is significantly more effective than using either peptide alone.
Normalizing the 'CJC Flush' Side Effect
A regular user of CJC-1295 confirmed that a 'flush,' along with changes in breathing and heart rate, is a common dose-dependent side effect. They mentioned that high doses (up to 1mg) frequently cause these symptoms but considered them a normal part of the experience.
CJC-1295 DAC Recommended for Long-Term Cycles
A user recommended CJC-1295 with DAC at doses of 2mg per week, describing it as a high-quality option for long-term cycles. They compared its value to other growth factors, suggesting it is an effective choice for those avoiding cheap, unreliable GH sources.
Dose-Dependent CJC-1295 Flush and Tachycardia
A user reported experiencing a sudden 'heat wave' or flushing sensation and an increased heart rate after administering a 600mcg dose of CJC-1295. These side effects were not present at doses below 200mcg.
GLP-1 Dominance Over Peptides
A user stacking GLP-1 medications with growth hormone peptides observed that the GLP-1 effects, such as appetite suppression, remain dominant. They suggested that the peptides do not overpower the effects of medications like Tirzepatide.
Long-term CJC/Ipamorelin User Reports Recovery Benefits
A user who has used CJC-1295 in various forms with Ipamorelin or GHRP-6 at least 10 times reported that the combination is effective for recovery. However, they noted that the stack did not provide a noticeable boost in energy or drive.
Euphoric Effects from CJC-1295/Ipamorelin Blend
A user reported using a CJC-1295 (no DAC) and Ipamorelin blend at a dosage of 200mcg of each peptide. They noted experiencing a "transient moderate euphoric head rush" immediately after injection and generally enjoyed the protocol.
Injury Recovery with CJC-1295/Ipamorelin Blend
A user found success with the CJC-1295/Ipamorelin blend for physical recovery, noting that several lingering injuries and health issues cleared up. Despite only injecting 3-4 times per week due to meal timing constraints, they still achieved positive results.
Planned Use for Body Composition Goals
A user planning a comprehensive performance-enhancing cycle included a combination of CJC-1295 DAC and Ipamorelin to be administered before bedtime. They aimed to use the stack alongside various anabolic steroids to achieve a target weight of 210-220 lbs while reducing body fat.
Adverse Skin Reactions and Flushing
A user reported experiencing negative physical reactions when using CJC-1295 (with or without Ipamorelin), even at very low dosages. Specifically, they suffered from face flushing and the development of hives.
Gentle Pituitary Boost with Minimal Downsides
A user described the combination of CJC-1295 (no DAC) and Ipamorelin as having typically no downsides. They noted that the stack provides a gentle boost to the pituitary gland to stimulate growth hormone production.
Efficacy Dependent on Fasting Protocols
A user suggested that combining CJC-1295 non-DAC and Ipamorelin is effective when administered while fasting. They noted that these peptides yield noticeable results in this specific context, whereas other growth hormone fragments may be ineffective on their own without proper fasting protocols.
90-Day Results: Muscle Fullness and Sleep Improvement
A user completed a 90-day cycle of the blend and reported significant body recomposition, including a noticeable increase in muscle fullness and a decrease in body fat. They also highlighted a drastic improvement in sleep quality and faster recovery times from workouts.
Recovery Benefits for Combat Sports and Functional Fitness
A practitioner of Jiu Jitsu and kettlebell training shared that the combination significantly improved their recovery and sleep. While they did not see massive muscle gains, they noted that the peptide helped them maintain intensity during high-volume training weeks.
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